This molecular test evaluates individuals for the germline Factor V Leiden variant (F5 c. 1601G7A, p.Arg534Gln; Legacy nomenclature G1691A), which is associated with an increased risk of venous thromboembolism.
Additional Test Information
Amniotic Fluid, Buccal Swabs, Cultured Amniocytes, CVS, DNA, EDTA Bone Marrow, EDTA Whole Blood
Additional Sample Requirements
Sample must be less than one month old when received in the laboratory.
3-5 mL EDTA Whole Blood or Bone Marrow (lavender top), 3-4 Buccal Swabs, 1 ug DNA at 50 ng/uL, 7-15 mL Amniotic Fluid, 5-10 mg CVS, 2-T25 flasks cultured amniocytes or CVS (2x10^6 minimum)
Fetal: Call Laboratory; Parental/Patient: 2 ml
PCR and Hybridization Probes