Genetic analysis is used to diagnose type 2A and 2B VWD in patients with abnormal multimer findings. VWF exon 28 sequence analysis is always performed; if negative, VWD Type 2A Additional Exons is performed at an additional charge.
Additional Test Information
Fetal: Amniotic Fluid, CVS, Cultured Amniocytes or Cultured CVS; Parental/Patient: EDTA Whole Blood (lavender top)
Fetal: 7-15 ml Amniotic Fluid or 5-10 mg CVS, backup culture of Amniocytes or CVS is highly recommended; Two T25 flasks Cultured Amniocytes or CVS (2x10^6 minimum); Parental/Patient: 3-5 ml
Fetal: Call Laboratory; Parental/Patient: 2 ml
Exon 28: 81403; 2A: 81406
PCR and Bi-directional DNA Sequencing