Also Known as
F9, Factor, FIX, Hemophilia B, Sequence Analysis
Sequence analysis of the F9 gene detects germline variants associated with mild, moderate, and severe hemophilia B, as well as Hemophilia B Leyden.
Additional Test Information
EDTA Whole Blood, EDTA Bone Marrow, DNA, Buccal Swabs, Amniotic Fluid, Cultured Amniocytes, Direct or Cultured CVS
3-5 mL EDTA Whole Blood or Bone Marrow (lavender top), 3-4 Buccal Swabs, >=1 ug DNA at >=50 ng/uL, 7-15 mL Amniotic Fluid, 5-10 mg CVS, 2-T25 flasks cultured amniocytes or CVS (2x10^6 minimum)
Fetal: Call Laboratory; Parental/Patient: 2 ml
Capture hybridization and Next Generation sequencing with supplementary PCR and bi-directional Sanger sequencing for quality and coverage.