Vaccine-Induced Immune Thrombotic Thrombocytopenia

Diagnostic Testing Options

• VITT Workup (HIT-like presentation): Thrombosis with Thrombocytopenia

  This workup includes the PF4 ELISA – IgG (Heparin-Dependent Platelet Antibody), with an automatic reflex (if PF4 ELISA results are non-negative) to concurrent SRA testing BOTH with and without unfractionated heparin.

  Order Code: 5515

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  Additional Testing Available (if clinically indicated)

  • Heparin-Induced Thrombocytopenia – PEA Order Code 5502

  If PF4 ELISA in non-negative locally, consider:

  • Concurrent SRA testing BOTH with and without unfractionated heparin Order Code: 5506
• VITT Orderables (ITP-like presentation): Thrombocytopenia without Thrombosis

  This workup initiates with:

  • Platelet Autoantibodies if patient platelet count is >30,000/µL Order Code: 5544
  • Platelet Antibody Identification Panel if patient platelet count is <30,000/µL Order Code: 5608

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  If there is further clinical indication, consider:

  • PF4 ELISA – IgG (Heparin-Dependent Platelet Antibody) Order Code: 5510
  • Drug-dependent Platelet Antibodies* Order Code: 9000

  *Call Versiti Client Services to discuss availability of vaccine when ordering Drug-dependent Platelet Antibodies: 800-245-3117, Option 1