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Michael Deininger Laboratory

Michael Deininger Laboratory at Versiti Blood Research Institute

Translational Research of Leukemia

The Deininger lab’s expertise focuses on translational research in leukemia, specifically the biology of myeloproliferative neoplasms and the development of molecular targeted therapies. We are especially interested in developing novel, anti-neoplastic targeted therapies in myeloid leukemia, as well as understanding the molecular mechanisms of cancer stem cell persistence and leukemia drug resistance.

Our lab orchestrates a multidisciplinary cancer research program, straddling genetics, biochemistry, molecular biology, pharmacology and biomedical engineering. We are proud of our vibrant team of scientists who strive to improve the diagnosis, deep analysis and therapeutics of myeloid leukemia.

Illustration showing normal blood in comparison to blood with leukemia.

Leukemic cells exhibit abnormal proliferation.

Article published by the Deininger laboratory featured on the cover of Blood, February 2022.

Deininger Lab’s new article featured on the journal cover of Blood

We are excited that a recent paper, MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common B-chain cytokine receptor endocytosis, published by the Deininger Laboratory was featured on the cover of the February, 2022 article of Blood magazine.

Read the full article.

Lab Updates and News

More News
  • Unlocking novel treatments for heart attacks and strokes

    April 8, 2022 | Brian Branchford, MD; Yiliang Chen, PhD;

  • Understanding blood clot lysis, or how clots break down

    March 16, 2022 | Lisa Baumann Kreuziger, MD, MS; Renren Wen, PhD; Brian Branchford, MD;

  • Improving outcomes for children with cancer

    February 10, 2022 | Weiguo Cui, MD, PhD; Matthew Kudek, MD;

Looking to Join the Lab Team?

Lab equipment and molecular structures image montage.


The Deininger lab’s expertise focuses on translational research of leukemia.

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Library with book shelves and tables.


Read a select list of Dr. Deiningers publications.

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Illustration showing leukemia blast and lyphatic pathology.


Michael Deininger lab team members.

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