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Pradhan-Sundd Lab

The Pradhan-Sundd Laboratory explores hepato-vascular cells in sickle cell disease and other hematological disorders.

Tirthadipa Pradhan-Sundd Laboratory at Versiti Blood Research Institute

Computer generated Sickle Cell blood cell illustration.

The Pradhan-Sundd Laboratory’s goal is to gain a better understanding of the involvement of hepato-vascular cells (liver sinusoidal endothelial cells, tissue resident macrophages and monocytes) in hematologic liver diseases. Our disease models include a humanized mouse model of sickle cell disease-induced acute and chronic liver injury, iron overload in the liver, murine models of hemolysis, vasculopathy, stressed erythrophagocytosis, and a mouse model of hemophilia.

 

Research

The Pradhan-Sundd lab’s research focuses on chronic organ injury and the processes of hepatic hemoglobin, heme and iron clearance in sickle cell disease.
 

Publications

Tirthadipa “Dipa” Pradhan-Sundd and her research team have been published in a number of prestigious scientific and medical journals.
 

Team

Get to know the members of the Pradhan-Sundd laboratory team at Versiti Blood Research Institute.
 

Image Gallery

Research images from the Pradhan-Sundd laboratory at Versiti Blood Research Institute.
10/8/2023

Congratulations Omika for your new post! We wish you all the very best from the Pradhan-Sundd lab.


8/28/2023

Congratulations to Ziming Li for his acceptance to NYU for post graduate studies!


2/20/2023

Congratulations Shweta! Our heart is swelled with joy as Shweta Gudapati got selected for both Temple and Stanford medical schools. She was the first undergrad of the Pradhan-Sundd Lab and worked with us for 3 years; published 3 papers and got many prestigous awards.


12/28/2022

Congratulations to Omika and Ziming for their poster presentations at the annual ASH meeting, 2022 held at NOLA.


2/26/2022

Congratulations to Ziming Li for his very first successful poster presentation at the Dept. of Biology Annual Undergraduate Symposium on his recent AJP-CP paper. Way to go Ziming!


2/26/2022

Pradhan-Sundd Lab is celebrating acceptance of full article at AJP-Cell Physiology!


2/26/2022

Shweta is selected for the final round of Goldwater Scholarship! Way to go Shweta!


7/18/2021

Shweta wins Capstone Grant from The Histochemical Society to study hepatic and extrahepatic sources of FVIII synthesis!


2/4/2021

Pradhan-Sundd lab is celebrating the acceptance of our article in Blood! Check it out.