Versiti - Versiti Comprehensive Center for Bleeding Disorders
 

Comprehensive Center for Bleeding Disorders (CCBD)

Versiti CCBD is a federally recognized hemophilia treatment center (HTC).

Where Breakthrough Science Meets Life-Changing Care

 

Versiti’s Comprehensive Center for Bleeding Disorders provides accessible, personalized care for patients with bleeding and clotting disorders. As southeastern Wisconsin's only federally funded Hemophilia Treatment Center, our board-certified hematologists lead multidisciplinary teams dedicated exclusively to conditions like hemophilia, von Willebrand disease, platelet function disorders, and thrombophilia. 

Specialized Expertise

Board-certified hematologists focusing exclusively on bleeding and clotting disorders

Gene Therapy Center

One of the nation's first centers delivering HEMGENIX gene therapy for hemophilia B

Comprehensive Support

Multidisciplinary teams addressing medical, emotional, and practical needs

Gene Therapy: A New Chapter in Hemophilia B Care

At Versiti Comprehensive Center for Bleeding Disorders, we recognize the immense potential of gene therapy. Designed to be one-time, durable therapies, these treatments can transform chronic conditions that require lifelong treatment into manageable ones. Versiti Comprehensive Center for Bleeding Disorders is home to specialized infrastructure and comprehensive care protocols necessary to bring these breakthrough therapies to our community with uncompromising clinical excellence. Our focused gene therapy team, including Dr. Malec and members of our pharmacy, nursing, nurse practitioner, and genetic counseling teams, help patients understand the treatment options available to them on an individual basis.

 
 

HEMGENIX is an FDA-approved gene therapy for adults with hemophilia B who currently use factor IX prophylaxis therapy, have experienced life-threatening bleeding, or have repeated serious bleeding episodes. Through a single intravenous infusion, HEMGENIX delivers a functional factor IX gene to liver cells, enabling the body to produce its own clotting factor. Clinical studies demonstrate that 94 percent of patients receiving HEMGENIX can discontinue regular factor IX infusions.

Meet Lynn Malec

 

Lynn Malec MD, MSc

Program Director
Versiti Comprehensive Center for Bleeding Disorders and Pharmacy

"We partner with patients through a transformative journey. Gene therapy requires sophisticated clinical judgment, comprehensive patient education, and meticulous long-term follow-up. At The Comprehensive Center for Bleeding Disorders, we've built our program around these principles, ensuring every patient receives the expert, coordinated care that makes transformation possible."

Cody's Journey: From Constant Vigilance to Freedom

 

"From 2014 to 2019, I endured four ankle surgeries because of advanced arthritis from hemophilia B," said Cody Gunst, a CCBD patient. "If gene therapy had existed then, I wouldn't have two fused ankles now. But this treatment changed everything that came after."

Before gene therapy, Cody required approximately four factor infusions per month — vigilance that shaped every aspect of daily life. Within 60 days of receiving HEMGENIX, Cody’s factor IX levels increased from less than 1 percent to more than 12 percent.

Is Gene Therapy Right for You?

Gene therapy may be appropriate for adults with hemophilia B who:
  • Currently require regular factor IX prophylaxis therapy
  • Have experienced a life-threatening hemorrhage
  • Have repeated serious spontaneous bleeding episodes
  • Are interested in reducing or eliminating regular infusions
  • Can commit to comprehensive long-term monitoring

The Comprehensive Center for Bleeding Disorders team believes deeply in treating the whole patient, not just a patient’s disorder. Our dedicated gene therapy experts, including pharmacists, nurses, nurse practitioners, genetic counselors, and your doctor, will work with you to determine whether gene therapy aligns with your clinical needs and treatment goals.

 

Our Approach to Specialized Care

 

Bleeding and clotting disorders require specialized expertise that goes beyond general hematology. At Versiti CCBD, our board-certified hematologists dedicate their practice exclusively to these complex conditions, developing the nuanced clinical judgment necessary for optimal diagnosis and treatment. This specialization means we recognize subtle presentations, anticipate complications, and personalize treatment.

We recognize that these conditions affect entire families, not just individual patients. We provide education, support, and resources for parents, siblings, partners, and caregivers, recognizing that family well-being has a direct impact on patient outcomes. Whether you're navigating a new diagnosis, managing complications, planning for surgery or exploring cutting-edge treatments like gene therapy, our team brings both sophisticated clinical knowledge and genuine partnership to every interaction.

Conditions We Treat

Hemophilia is an inherited bleeding disorder caused by a deficiency or dysfunction of blood-clotting factors. Hemophilia A results from factor VIII deficiency, while hemophilia B stems from factor IX deficiency. We provide comprehensive hemophilia management, from prophylactic factor replacement to breakthrough therapies like gene therapy for hemophilia B. Our team helps patients navigate treatment options, optimize dosing regimens, manage bleeding episodes, and maintain joint health through both traditional factor replacement and extended half-life products.

Von Willebrand disease is the most common inherited bleeding disorder, caused by a deficiency or dysfunction of von Willebrand factor, a protein essential for normal blood clotting. Accurate diagnosis requires sophisticated laboratory testing and clinical expertise, both of which our team provides. We distinguish between disease types and subtypes, enabling precise treatment selection including desmopressin therapy, von Willebrand factor replacement products, and strategies for managing bleeding during surgery, dental procedures, and childbirth.

Platelet function disorders affect the ability of platelets to properly adhere, activate, and aggregate at sites of blood vessel injury. We provide specialized platelet function testing to accurately diagnose these often-subtle conditions. Our treatment approaches are highly individualized, taking into account each patient's specific platelet defect, bleeding history, and lifestyle factors.

Thrombophilia refers to conditions that increase the risk of developing abnormal blood clots in veins or arteries. These conditions can be inherited, such as factor V Leiden or a prothrombin gene mutation, or acquired, like antiphospholipid syndrome. We provide comprehensive evaluation to identify underlying clotting disorders, helping patients and their physicians understand clot risk and make informed decisions about anticoagulation therapy while balancing clot prevention with bleeding risk.

We diagnose and manage rare bleeding disorders, including deficiencies of factors I, II, V, VII, X, XI, and XIII, as well as combined factor deficiencies and rare platelet disorders like Bernard-Soulier syndrome and Glanzmann thrombasthenia. Our team has expertise in these uncommon conditions, providing accurate diagnosis, personalized treatment planning and connections to national and international rare disease networks.

For Referring Physicians

When your patients face complex bleeding or clotting disorders, you need a collaborative partner who provides specialized expertise while keeping you informed and involved in care decisions. At Versiti CCBD, we view ourselves as an extension of your care team, providing the sophisticated hematology and genetic counseling expertise your patients need while maintaining clear and consistent communication throughout their care journey.

Why Refer to Versiti Comprehensive Center for Bleeding Disorders

Our hematologists focus exclusively on bleeding and clotting disorders, bringing depth of experience that enables nuanced diagnosis, sophisticated treatment selection, and anticipation of complications. We provide specialized laboratory testing, including complex factor assays, platelet function testing, and thrombophilia panels.

Your patients benefit from our multidisciplinary team, all coordinating seamlessly to address every aspect of bleeding disorder management. We provide timely consultation notes, treatment recommendations, and ongoing updates, ensuring you remain informed about your patients' specialized care.

We welcome referrals for patients with known or suspected hemophilia, von Willebrand disease, platelet function disorders, rare bleeding disorders, thrombophilia, or recurrent clotting events, unexplained bleeding despite normal standard testing, and patients interested in gene therapy evaluation.

How to Refer

Call CCBD at 414-257-2424 to discuss your patient and schedule an appointment. We typically schedule new patients within two to four weeks, with urgent consultations available sooner.

 
Comprehensive Center for Bleeding Disorders
Office Phone and Fax Information
  • 414-257-2424
  • 414-937-6580
  • Comprehensive Center for Bleeding Disorders

    8739 Watertown Plank Road
    Wauwatosa, WI 53226

    Office Hours:

    Monday thru Friday, 8:30 a.m. to 4:30 p.m.


    24-Hour Coverage

    For Pediatric Patients Call:
    Children's Hospital of WI 414-266-2000.

    For Adult Patients Call:
    Froedtert Hospital: 414-804-3000.
    Ask to speak to the Hematologist on call.

    Specialty Pharmacy

    Joe Bailey, PharmD, Pharmacy Operations Manager
    Specialty Pharmacy and Drug Distribution
    414-937-6436

     
    Adult Hematology

    The Adult Hematology Program cares for patients with benign hematologic disorders at Froedtert Hospital and Children’s Wisconsin.

     
    Patient Pharmacy

    Versiti Comprehensive Center for Bleeding Disorders offers an onsite pharmacy for patients being treated for bleeding and clotting disorders.

     
    Lynn Malec, MD, MSc

    CCBD Medical Director

    Hematologist

     
    Veronica Flood, MD

    Hematologist

     
    Ken Friedman, MD

    Hematologist

     
    Rowena Punzalan, MD

    Hematologist

     
    Brian Branchford, MD

    Hematologist

     
    Nicole Liberio, MD

    Hematologist

     
    Bethany Pierringer

    Nurse Practitioner

     
    Kriti Behl Stefan

    Nurse Practitioner

     
    Angelica Chironis

    Outreach and Home Care Coordinator

     
    Tiffini Mueller, RN

    Manager/Registered Nurse

     
    Sheri Robbins

    Social Worker

     
    Traci Knebes

    Social Worker

     
    Paige Woltring, RN

    Nurse Coordinator

     
    Michelle Dobratz, RN

    Nurse Coordinator

     
    Meagan Ross, RN

    Nurse Coordinator

     
    Monica Thom, RN

    Nurse Coordinator

     
    Laney Tarantino

    Nurse Coordinator

     
    Trisa Hayden

    Senior Administrator

     
    Michele Thiry

    Senior Clinical Service Specialist

     
    Miranda Thom

    Senior Clinical Service Specialist

     
    Jeffrey Karst, PhD

    Psychology Services

     
    Rebecca Kohl

    Physical Therapist

     
    Stefanie Dugan, MS, LCGC

    Genetics Counselor

     
    Elizabeth Palmer, MS, LCGC

    Genetics Counselor

     
    Siomara Santana
     
    Trisa Hayden

    Senior Administrator

     
    Michele Thiry

    Senior Clinical Service Specialist

     
    Miranda Thom

    Senior Clinical Service Specialist

     
    Yousra Abuasi

    Pharmacist

     
    Mark Santiago

    Pharmacy Coordinator

     
    Amber Corrao

    Pharmacy Coordinator

     
    Megan Lemanczyk

    Clinical Regulatory Coordinator

     
    Karen Stephany

    Senior Research Coordinator

     
    Courtney Conway

    Supervisor, Clinical Trial & Research Office

     
    Erin Wallisch

    Clinical Research Coordinator

     
    Jacqueline Westerdahl

    Senior Research Coordinator

     
    Marian Wilkerson

    Registered Dietitian

     

    Remembering Dr. Joan Gill

    As a “lifespan clinic,” Versiti Comprehensive Center for Bleeding Disorders’ pediatric and adult hematologists are dedicated to caring for patients of all ages. Our longtime medical Director, Joan Gill, MD, established CCBD as a center of excellence committed to improving the lives of patients. Today, our staff of physicians, nurse practitioners, nurses, physical therapist, genetic counselors, social workers, psychologist, pharmacy specialists and research coordinators continue this legacy of excellence in Dr. Gill’s memory.

    Note: Bleeding and clotting disorders can be very serious. Do not use this website for medical advice or in the event of a medical emergency. The information posted here is intended for general information only. In the event of an emergency, call 911 or your local emergency assistance number. For medical advice and care, including diagnosis and treatment, consult a medical doctor.

     
    Adult Hematology Program
    The Adult Hematology Program cares for patients with benign hematologic disorders at Froedtert Hospital and Children’s Wisconsin.
     
    Patient Pharmacy
    Versiti Comprehensive Center for Bleeding Disorders offers an onsite pharmacy for patients being treated for bleeding and clotting disorders.
     
    Video Gallery
    Browse Versiti’s video gallery, a collection of videos featuring employees, blood donors, organ and tissue donor families, and patients whose lives have been impacted by our mission.
     
    Impact Stories
    Your blood, organ and tissue, and other donations directly impact lives in your community. Read a few of the examples of some of the lives that have been changed for the better.