Versiti - Versiti Immunohematology Reference Laboratories
Explore our service lines

ImmunohematologyReference Laboratories

Expert serologic and molecular testing paired with consultative interpretation to support safe, confident transfusion decisions.

Experts in resolving complex immunohematology cases

Versiti’s Immunohematology Reference Laboratories (IRL) help hospitals resolve the most complex red cell transfusion challenges. Our teams include renowned physicians and the nation’s largest group of SBB-certified technologists, pairing deep serologic expertise with advanced molecular immunohematology to interpret layered findings and bring clarity to difficult cases. Accredited by the American Association of Blood Banks (AABB), Versiti IRLs support safe, compatible blood selection for patients with complex transfusion needs.

Contact Us
  • 800-245-3117 x 6250
  • What Our Reference Laboratories Provide

    • 24/7 laboratory coverage, including weekends and holidays
    • Accessible, professional staff who support hospital transfusion services
    • Serologic investigation and consultation for red cell transfusion-related challenges
    • Procurement of antigen-negative red blood cell units
    • Coordination of rare donor unit requests through the American Rare Donor Program (ARDP)

    Specialists in Immune-Mediated Red Cell Destruction

    Versiti’s IRLS are trusted partners in evaluating immune-mediated red cell destruction, bringing deep serologic expertise to some of the most challenging hemolytic cases. Our specialists help hospitals clarify complex findings in autoimmune, DAT-negative, and drug-induced hemolytic anemia, supporting accurate diagnosis and safer transfusion decisions for high-risk patients.

    Red Cell Genotyping Expertise

    Versiti physicians and laboratory professionals bring more than 50 years of experience helping blood banks and clinicians solve complex transfusion medicine challenges. Versiti’s red cell genotyping services deliver results quickly and cost effectively, supporting confident patient care while helping reduce alloimmunization, improve red cell utilization, and potentially lower donor screening costs.

    IRL technician working on serologic testing.

    IRL Tests and Services

    Versiti’s IRLs help hospitals resolve the most complex red cell transfusion challenges. Our teams include renowned physicians and the nation’s largest group of SBB-certified technologists, pairing deep serologic expertise with advanced molecular immunohematology to interpret layered findings and bring clarity to difficult cases. Accredited by the American Association of Blood Banks (AABB), Versiti IRLs support safe, compatible blood selection for patients with complex transfusion needs.

    Antigen Negative Blood

    Versiti maintains one of the nation’s largest donor genotyping programs, with more than 300,000 genotyped donors supporting most antigen-negative and rare blood needs. For the few requests that cannot be met internally, Versiti coordinates through the American Rare Donor Program.

    Expert Consultations

    Versiti provides 24/7 medical consultative services through a physician team of more than 20 transfusion medicine specialists. This consultative expertise spans routine and complex cases, including bleeding and platelet disorders, transplantation, therapeutic apheresis, and thrombolytic care.

    Red Cell Antibody Investigations

    Versiti’s IRLs evaluate discrepant serologic results, including autoantibodies, drug-dependent antibodies, rare antigen antibodies, hemolytic disease of the newborn, and transfusion reactions, ranging from single to complex antibody cases.

    Serologic Troubleshooting Investigations

    Versiti’s IRLs evaluate ABO discrepancies and red cell typing challenges, including weak antigen expression and polyagglutination. Services include donor and patient phenotype and genotype testing, plus prenatal ABO/Rh, antibody identification, and titers.

    Frequently Asked Questions

    What are the basic shipping requirements for samples?

    Diagnostic samples and/or infectious substances must be packaged in compliance with Department of Transportation (DOT), International Air Transport Association (IATA), and the specific requirements of the overnight carrier used.

    Is Versiti fully accredited and licensed?

    Versiti, Inc. holds a number of nationwide and statewide certifications, registrations, accreditations and licenses from the FDA, state health departments and more. See all accreditations.

    Any other questions we can answer for you?
    Contact Us