Versiti - Chimerism Testing for Engraftment

Chimerism Testing For Engraftment

Rapid and highly sensitive chimerism lab tests for post-transplant monitoring.

What is Chimerism?

Chimerism occurs when a person’s body contains two different sets of DNA. Versiti Diagnostic Labs offers sophisticated chimerism testing for post-transplant patients, including those who received solid organ transplantation, bone marrow transplantation and cellular therapy treatments.  

Versiti Diagnostic Laboratories’ expertise includes:

  • More than 30 years of chimerism test experience in post-transplant monitoring and cell therapy
  • Four-day testing turnaround time with low limit of detection
  • Chimerism testing on cell enrichment types CD3, CD19, CD33, CD56
Contact Information
  • 800-245-3117 x 6250
  • We support our transplant partners by helping to monitor the relative amounts of recipient and donor cells after transplantation. Important clinical events in allogenic bone marrow transplantation, such as engraftment, relapse and the effects of post-transplant therapies, can be monitored on a molecular level by using inherent genetic differences between recipients and donors.

     Versiti Diagnostic Labs’ genetic chimerism testing has proven reliability, demonstrated by consistent, accurate, precise performance in proficiency programs.

    Enriched Cell Populations

    Enriched cell populations can also be used to monitor patients following hematopoietic stem cell transplant for more precise detection of changes in transplant dynamics. Testing for the following cell subtypes is available:

    Cell MarkerCell Subset
    CD19B cells
    CD56Natural Killer (NK) cells

    Indications For Testing

    • Monitor hematopoietic reconstruction following allogenic bone marrow transplantation
    • Monitor effects of post-transplant therapies
    • Monitor minimal residual disease or relapse
    Diagnostic Laboratories
    Diagnostic laboratory services including HLA testing, donor testing, immunohematology reference lab testing, hematology testing and more.
    Human Leukocyte Antigen (HLA) Typing
    Versiti Diagnostic Labs’ Histocompatibility Lab provides human leukocyte antigen (HLA) typing for solid organ transplant and HCT patients.
    Our Experts
    Research investigators, postdoctoral fellows and laboratory staff at Versiti Blood Research Institute and Diagnostic Laboratories.